Monocyte/HDL-cholesterol ratio predicts the definite stent thrombosis after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction


Cetin E. H. O. , Cetin M. S. , Canpolat U. , Aydin S., Topaloglu S., Aras D., ...Daha Fazla

BIOMARKERS IN MEDICINE, cilt.9, sa.10, ss.967-977, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9 Konu: 10
  • Basım Tarihi: 2015
  • Doi Numarası: 10.2217/bmm.15.74
  • Dergi Adı: BIOMARKERS IN MEDICINE
  • Sayfa Sayıları: ss.967-977

Özet

Aim: We investigated the predictive value of monocyte count to HDL ratio (M/H ratio) for stent thrombosis (ST) in ST elevation myocardial infarction (STEMI). Patients & methods: 1170 STEMI patients treated with primary PCI were followed-up for a median of 37.2 months. Results: During follow-up, 112 patients were diagnosed as 'definite' ST. The rate of ST was significantly highest in the third M/H ratio tertile. In Cox regression analysis, adjusted for other factors, having an M/H ratio in third tertile had a 2.2-fold increased risk of ST. Kaplan-Meier analysis revealed the higher occurrence of ST in the third tertile compared with others (p < 0.001). Conclusion: M/H ratio as a novel marker of inflammation seemed to be an independent predictor of ST in STEMI patients.