Context: Pilonidal sinus is a disease which is very common, especially in men and usually located in sacrococcygeal area. However, the disease can be also seen in rare localizations such as umblicus, forehead, scalp, clitoris, interdigital area and axilla. In the etiology of pilonidal sinus, acquired theory is accepted by most of surgeons instead of the congenital one. Case report: In the present study, we purposed to report our case of hirsute Turkish women aged 25 having axillary pilonidal sinus. After application of total surgical excision with eliptical skin incision, histopathological evaluations confirmed the prediagnosis of axillary pilonidal sinus. The patient was lost to follow-up and neither recurrens nor distance metastasis has been detected during 36 months. Conclusions: In our opinion; surgical therapy of axillary pilonidal sinus, allows to complete resection in addition to absolute histopathological diagnoses and it may be an appropriate choice of treatment especially for the disease having one or two sinuses.