Polyphenolic compounds from Geranium pratense and their free radical scavenging activities.

Akdemir Z., Tatli İ. İ., Saracoglu I., Ismailoglu U., Sahin-Erdemli I., Calis I.

Phytochemistry, cilt.56, sa.2, ss.189-93, 2001 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 56 Sayı: 2
  • Basım Tarihi: 2001
  • Doi Numarası: 10.1016/s0031-9422(00)00367-8
  • Dergi Adı: Phytochemistry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.189-93
  • Anahtar Kelimeler: Geranium pratense subsp finitimum (Woronow) Knuth, Geraniaceae, flavonoid, myricetin 3-O-(2 '-O-galloyl)-beta-D-glucopyranoside, (-)-6-chloroepicatechin, free radical scavenger, ENDOTHELIUM-DEPENDENT RELAXATION, RAT AORTIC RINGS, REPERFUSION INJURY, DYSFUNCTION, GLYCOSIDES, FLAVONOIDS, IMPAIRMENT
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Two new polyphenolic compounds, myricetin 3-O-(2"-O-galloyl)-beta -D-glucopyranoside and (-)-6-chloroepicatechin, were isolated from the aerial parts of Geranium pratense subsp. finitimum (Woronow) Knuth, along with three known polyphenolic compounds [quercetin 3-O-(2"-O-galloyl)-beta -D-glucopyranoside, quercetin 3-O-(2"-O-galloyl)-beta -D-galactopyranoside, methyl gallate] and tryptophan. Quercetin 3-O-beta -D-glucopyranoside, quercetin 3-O-beta -D-galactopyranoside, quercetin 3-O-(2"-O-galloyl)-beta -D-glucopyranoside and quercetin 3-O-(2"-O-galloyl)-beta -D-galactopyranoside were found to be effective against free radical induced impairment of endothelium-dependent relaxation in isolated rat aorta. (C) 2001 Elsevier Science Ltd. All rights reserved.