Stenotrophomonas rnaltophilia bacteremia in children - A 10-year analysis


BÜYÜKCAM A. , BIÇAKÇIGİL A. , Cengiz A. B. , SANCAK B. , CEYHAN M. , KARA A.

ARCHIVOS ARGENTINOS DE PEDIATRIA, cilt.118, sa.3, 2020 (SCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 118 Konu: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5546/aap2020.eng.e317
  • Dergi Adı: ARCHIVOS ARGENTINOS DE PEDIATRIA

Özet

Stenotrophomonas tnaltophilia is a multidrug-resistant, Grarnnegative, andbiofilm-forming pathogen. Information is limited concerning S. maltophilia bacteremia in children. Clinical data and microbiological test results collected ma tertiary children's hospital over a ten-year period were reviewed. Children 0-18 years old who had positive clinical specimen, blood and/or catheter cultures were included. We identified 20 S. maltophilia isolates from 12 pediatric patients with confirmed infections. The median age was 28 months (range: 3.1-1873). The rate of previous use of antimicrobial therapy was 83 5.. The median antibioticnu rnber was 3 (range: 0 7) within30 days prior to onset of S. maltophilut bacteremia. Catheter related infection was the main infectious source (66.6 %). The mortality rate was 33.3 %). The death of two non-surx,ivors was associated with pneumonia. S. mallophilia should be considered a breakthrough agent for bacteremia in children with underlying disease exposed to broad-spectrum antibiotics during long-term hospitalization.