Performance of indirect immunofluorescence test and immunoblot tests in the evaluation of antinuclear and antimitochondrial antibodies


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Ozturk O., DEMİRCİ DOS SANTOS DUARTE S., BALABAN H. Y., ŞİMŞEK H., Sener B.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.52, no.5, pp.1697-1703, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 5
  • Publication Date: 2022
  • Doi Number: 10.55730/1300-0144.5512
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1697-1703
  • Keywords: Autoimmune hepatitis, primary biliary cholangitis, immunofluorescence test, immunoblot test, PRIMARY BILIARY-CIRRHOSIS, AUTOIMMUNE LIVER-DISEASE, CLINICAL-SIGNIFICANCE, AUTOANTIBODIES, HEPATITIS, DIAGNOSIS, ANTIGENS, SEROLOGY, ASSAY, SERA
  • Hacettepe University Affiliated: Yes

Abstract

Background/aim: Antinuclear antibodies (ANA) and antimitochondrial antibodies (AMA) have essential markers for the diagnosis of autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC). These autoantibodies are detecting different laboratory methods. In this study, we studied the diagnostic performance of used methods in detecting ANA and AMA.