Reactogenicity and immunogicity of a new measles-mumps-rubella vaccine containing RIT 4385 mumps virus strain in healthy Turkish children

Kanra G., Ceyhan M., Ozmert E.

TURKISH JOURNAL OF PEDIATRICS, cilt.42, sa.4, ss.275-277, 2000 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42 Sayı: 4
  • Basım Tarihi: 2000
  • Dergi Adı: TURKISH JOURNAL OF PEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.275-277
  • Hacettepe Üniversitesi Adresli: Hayır

Özet

A total of 44 children aged between 15-18 months were randomly vaccinated either with a new measles-mumps-rubella (MMR) vaccine (Priorix(R), SmithKline Beecham) or a commercially available MMR vaccine (MMR-II(R), Merck) to compare the reactogenicity and immunogenicity. No local symptoms or fever was reported. Seroconversion rates of the study vaccine were 100, 95 and 100 percent for measles, mumps and rubella, respectively. The seroconversion rates for the control vaccine were 100, 94.7 and 95.5 percent, respectively. The geometric mean titers (GMT's) for the study and control groups were 1695, 95, 58; and 2198, 1183 and 47; respectively.