Reactogenicity and immunogicity of a new measles-mumps-rubella vaccine containing RIT 4385 mumps virus strain in healthy Turkish children


Kanra G., Ceyhan M., Ozmert E.

TURKISH JOURNAL OF PEDIATRICS, vol.42, no.4, pp.275-277, 2000 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 4
  • Publication Date: 2000
  • Journal Name: TURKISH JOURNAL OF PEDIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.275-277
  • Hacettepe University Affiliated: No

Abstract

A total of 44 children aged between 15-18 months were randomly vaccinated either with a new measles-mumps-rubella (MMR) vaccine (Priorix(R), SmithKline Beecham) or a commercially available MMR vaccine (MMR-II(R), Merck) to compare the reactogenicity and immunogenicity. No local symptoms or fever was reported. Seroconversion rates of the study vaccine were 100, 95 and 100 percent for measles, mumps and rubella, respectively. The seroconversion rates for the control vaccine were 100, 94.7 and 95.5 percent, respectively. The geometric mean titers (GMT's) for the study and control groups were 1695, 95, 58; and 2198, 1183 and 47; respectively.