Gestational Outcomes of Pregnant Women with Unilateral Congenital Renal Agenesis

Fadiloglu E., Zaim O. C., ÇAĞAN M., Unal C., Beksac M. S.

Fetal and Pediatric Pathology, vol.41, no.4, pp.551-557, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 4
  • Publication Date: 2022
  • Doi Number: 10.1080/15513815.2020.1856245
  • Journal Name: Fetal and Pediatric Pathology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, EMBASE, MEDLINE
  • Page Numbers: pp.551-557
  • Keywords: unilateral congenital renal agenesis, preterm birth, preeclampsia, congenital anomaly, perinatal morbidity
  • Hacettepe University Affiliated: Yes

Abstract

© 2020 Taylor & Francis Group, LLC.Objective We evaluated if there were more adverse gestational outcomes of pregnant women with unilateral congenital renal agenesis (UCRA). Study design: This single center retrospective case–control study compared maternal complications and neonatal outcomes from 25 women with UCRA to the outcomes of 125 women with two kidneys. Results: UCRA women had lower gestational weeks at birth and higher rates of preterm delivery (p = 0.004 and <0.001; respectively). Mothers had higher rates of preeclampsia and newborns with congenital anomalies and neonatal intensive care unit (NICU) admission (p = 0.009, 0.042, and 0.039; respectively). Unadjusted odds ratios were significantly higher for preterm delivery and for any APGAR score of <7 at the first 10 min and preeclampsia [OR (95% CI):13.5 (4.66–39.05), 31 (3.44–279.32) and 5.76 (1.33–24.84), respectively]. Conclusion: Maternal UCRA is a risk factor for less optimal obstetric and neonatal outcomes.