Interaction of rat lung SSAO with the novel 1-N-substituted thiocarbamoyl-3-substituted phenyl-5-(2-pyrolyl)-2-pyrazoline derivatives


Yabanoglu S., Ucar G., Gokhan N., Salgin Goksen U., Yesilada A., Bilgin A. A.

JOURNAL OF NEURAL TRANSMISSION, vol.114, no.6, pp.769-773, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 114 Issue: 6
  • Publication Date: 2007
  • Doi Number: 10.1007/s00702-007-0686-8
  • Journal Name: JOURNAL OF NEURAL TRANSMISSION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.769-773
  • Hacettepe University Affiliated: No

Abstract

Interactions of twelve new synthesized 1-N-substituted thiocarbamoyl-3-substituted phenyl-5-pyrolyl-2-pyrazoline derivatives with rat lung semicarbazide-sensitive amine oxidase (SSAO) were assessed. Pyrazoline derivatives were synthesized according to previous methods and SSAO was purified from the crude microsomal fractions of rat lung.