Interaction of rat lung SSAO with the novel 1-N-substituted thiocarbamoyl-3-substituted phenyl-5-(2-pyrolyl)-2-pyrazoline derivatives

Yabanoglu, S.; Ucar, G.; Gokhan, N.; Salgin Goksen, U.; Yesilada, A.; Bilgin, A.

doi:10.1007/s00702-007-0686-8

Interaction of rat lung SSAO with the novel 1-N-substituted thiocarbamoyl-3-substituted phenyl-5-(2-pyrolyl)-2-pyrazoline derivatives

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Yabanoglu S., Ucar G., Gokhan N., Salgin Goksen U., Yesilada A., Bilgin A. A.

JOURNAL OF NEURAL TRANSMISSION, vol.114, no.6, pp.769-773, 2007 (SCI-Expanded)

Publication Type: Article / Article
Volume: 114 Issue: 6
Publication Date: 2007
Doi Number: 10.1007/s00702-007-0686-8
Journal Name: JOURNAL OF NEURAL TRANSMISSION
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.769-773
Hacettepe University Affiliated: No

Abstract

Interactions of twelve new synthesized 1-N-substituted thiocarbamoyl-3-substituted phenyl-5-pyrolyl-2-pyrazoline derivatives with rat lung semicarbazide-sensitive amine oxidase (SSAO) were assessed. Pyrazoline derivatives were synthesized according to previous methods and SSAO was purified from the crude microsomal fractions of rat lung.