The importance of proteinuria in preeclampsia and its predictive role in maternal and neonatal outcomes
HYPERTENSION IN PREGNANCY, vol.38, no.2, pp.111-118, 2019 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 38 Issue: 2
- Publication Date: 2019
- Doi Number: 10.1080/10641955.2019.1590718
- Journal Name: HYPERTENSION IN PREGNANCY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.111-118
- Hacettepe University Affiliated: Yes
Abstract
Objective: To evaluate impact of 24-h proteinuria level in preeclampsia on maternal/perinatal outcomes. Methods: Singleton pregnancies with preeclampsia delivered after 24 weeks of gestation were included. Patients were divided into mild (0.3 to <2 g) (n=72), severe (2 to <5 g) (n=30), and massive (>= 5 g) (n=24) proteinuria groups, and cut-off values of 24-h proteinuria for composite adverse maternal and neonatal outcomes were calculated. Results: Twenty-four hour proteinuria level cut-offs for composite adverse outcomes were 3275 mg (72.2% sensitivity, 85.6% specificity) and 2395 mg (72.7% sensitivity, 78% specificity) respectively. Conclusion: Severe and massive proteinuria were related to poor maternal, perinatal, and neonatal outcomes.