The importance of proteinuria in preeclampsia and its predictive role in maternal and neonatal outcomes


TANAÇAN A. , FADILOĞLU E. , BEKSAÇ M. S.

HYPERTENSION IN PREGNANCY, cilt.38, sa.2, ss.111-118, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Konu: 2
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1080/10641955.2019.1590718
  • Dergi Adı: HYPERTENSION IN PREGNANCY
  • Sayfa Sayıları: ss.111-118

Özet

Objective: To evaluate impact of 24-h proteinuria level in preeclampsia on maternal/perinatal outcomes. Methods: Singleton pregnancies with preeclampsia delivered after 24 weeks of gestation were included. Patients were divided into mild (0.3 to <2 g) (n=72), severe (2 to <5 g) (n=30), and massive (>= 5 g) (n=24) proteinuria groups, and cut-off values of 24-h proteinuria for composite adverse maternal and neonatal outcomes were calculated. Results: Twenty-four hour proteinuria level cut-offs for composite adverse outcomes were 3275 mg (72.2% sensitivity, 85.6% specificity) and 2395 mg (72.7% sensitivity, 78% specificity) respectively. Conclusion: Severe and massive proteinuria were related to poor maternal, perinatal, and neonatal outcomes.