The importance of proteinuria in preeclampsia and its predictive role in maternal and neonatal outcomes

TANAÇAN A., FADILOĞLU E., BEKSAÇ M. S.

HYPERTENSION IN PREGNANCY, vol.38, no.2, pp.111-118, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.1080/10641955.2019.1590718
  • Journal Name: HYPERTENSION IN PREGNANCY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.111-118
  • Hacettepe University Affiliated: Yes

Abstract

Objective: To evaluate impact of 24-h proteinuria level in preeclampsia on maternal/perinatal outcomes. Methods: Singleton pregnancies with preeclampsia delivered after 24 weeks of gestation were included. Patients were divided into mild (0.3 to <2 g) (n=72), severe (2 to <5 g) (n=30), and massive (>= 5 g) (n=24) proteinuria groups, and cut-off values of 24-h proteinuria for composite adverse maternal and neonatal outcomes were calculated. Results: Twenty-four hour proteinuria level cut-offs for composite adverse outcomes were 3275 mg (72.2% sensitivity, 85.6% specificity) and 2395 mg (72.7% sensitivity, 78% specificity) respectively. Conclusion: Severe and massive proteinuria were related to poor maternal, perinatal, and neonatal outcomes.