MULTIPLE SCLEROSIS AND RELATED DISORDERS, cilt.10, ss.14-21, 2016 (SCI-Expanded)
Background: Multiple sclerosis can impair cognition from the early stages and has been shown to be associated with gray matter damage in addition to white matter pathology. Objectives: To investigate the profile of cognitive impairment in clinically isolated syndrome (CIS), and the contribution of cortical inflammation, cortical and deep gray matter atrophy, and white matter lesions to cognitive decline.