A Case of Nasal Glial Heterotopia That Can Be Misdiagnosed as Storiform Patterned Sclerotic Fibroma/Collagenoma
TURKISH JOURNAL OF PATHOLOGY, vol.40, no.2, pp.134-137, 2024 (ESCI, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 40 Issue: 2
- Publication Date: 2024
- Doi Number: 10.5146/tjpath.2023.13053
- Journal Name: TURKISH JOURNAL OF PATHOLOGY
- Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
- Page Numbers: pp.134-137
- Hacettepe University Affiliated: Yes
Abstract
Objective: Nasal glioma, also known as nasal glial heterotopia, is a rare tumor -like lesion that often affects newborns or infants with no hereditary predisposition. Case Report: A 4-year-old child with a growth on the nasal dorsum since birth was diagnosed with nasal glial heterotopia/nasal glioma. The lesion showed a sclerotic fibroma/collagenoma-like storiform pattern with entrapped glial tissue that was S100 and GFAP positive. Conclusion: When a biopsy of the nasal dorsum demonstrates sclerotic microscopic findings with a storiform pattern, nasal glioma should be considered before making a diagnosis in the collagen-rich tissue spectrum (collagenoma or Gardner's fibroma), and an immunohistochemical panel should be requested to demonstrate the presence of an unrecognized light microscopically visible glial component.