Molecularly Imprinted SPR Sensor for Sensitive and Selective Detection of Pb2+-Ions
IEEE Sensors Journal, cilt.26, sa.19, ss.28330-28337, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 26 Sayı: 19
- Basım Tarihi: 2026
- Doi Numarası: 10.1109/jsen.2026.3723949
- Dergi Adı: IEEE Sensors Journal
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Aerospace Database, Compendex, INSPEC, Materials Science & Engineering Collection (ProQuest), Technology Collection (ProQuest)
- Sayfa Sayıları: ss.28330-28337
- Anahtar Kelimeler: Heavy metal ions, ion-imprinting, molecularly imprinted polymers (MIPS), Pb2+-ions detection, surface plasmon resonance (SPR)
- Hacettepe Üniversitesi Adresli: Evet
Özet
Lead contamination poses a significant risk to environmental and human health, necessitating sensitive and reliable detection strategies. Here, a Pb2+-ion-imprinted surface plasmon resonance (SPR) sensor was developed by constructing a coordination-driven recognition layer directly on a gold surface. Surface characterization confirmed the successful formation of the imprinted polymeric layer and the presence of metal–ligand interactions within the polymer matrix. The sensor enables real-time detection of Pb2+-ions over the 5–100 ppb range, with a low detection limit (LOD = 3.079 ppb) and quantification limit (LOQ = 9.331 ppb) and good linearity. The binding behavior follows the Freundlich isotherm, indicating heterogeneous recognition sites generated during imprinting process. Selectivity studies demonstrate that Pb2+-ions recognition is governed by coordination-based interactions, allowing effective discrimination against competing metal ions. The sensing performance remains stable in artificial wastewater, highlighting robustness in complex matrices. These results present a reliable and sensitive SPR platform for real-time monitoring of trace-level Pb2+-ions, offering strong potential for environmental applications.