Trefoil factor expression graft-versus-host disease of in biliary epithelium of the liver after allogeneic hematopoietic cell transplantation

Idilman R., Erden E., Arat M., Soydan E., Erkan O., Kuzu I., ...More

TRANSPLANTATION, vol.80, no.8, pp.1099-1104, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 80 Issue: 8
  • Publication Date: 2005
  • Doi Number: 10.1097/01.tp.0000179151.55881.a7
  • Journal Name: TRANSPLANTATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1099-1104
  • Keywords: graft-versus-host disease, trefoil peptides, cholestatic liver disease, hematopoietic cell transplantation, biliary epithelial cell, BONE-MARROW-TRANSPLANTATION, PEPTIDES, RISK, TFF1
  • Hacettepe University Affiliated: No

Abstract

Background. The aims of this study were to determine the presence of trefoil factor family-3 (TFF3) expression in biliary epithelial cells (BECs) of chronic graft-versus-host disease (cGVHD) of the liver after allogeneic hematopoietic cell transplantation, to compare such expression in chronic liver diseases (CLD) with/without predominantly biliary disease, and to assess the effect of bile duct injury on the degree of TFF3 expression in BECs of cGVHD.