Molecular mechanisms of signal transduction: Epidermal growth factor receptor family, Vascular endothelial growth factor family, Kit, Platelet-derived growth factor receptor, Ras

Erman, MUSTAFA

Molecular mechanisms of signal transduction: Epidermal growth factor receptor family, Vascular endothelial growth factor family, Kit, Platelet-derived growth factor receptor, Ras

Atıf İçin Kopyala

Erman M.

JOURNAL OF BUON, cilt.12, 2007 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 12
Basım Tarihi: 2007
Dergi Adı: JOURNAL OF BUON
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Hacettepe Üniversitesi Adresli: Evet

Özet

One of the major mechanisms of communication between cells is the binding of polypeptide ligands to cell surface receptors possessing tyrosine kinase (TK) activity. Though many actions of these receptors involve physiological processes, Perturbation of TK signaling can result in malignant transformation.