Posterior reversible encephalopathy syndrome (PRES) has been defined as a neurologic disorder with distinct radiologic findings demonstrating lesions in the subcortical white matter at posterior circulation territory. Several authors suggested alternative descriptive terms for this syndrome as atypical radiologic features have been described more frequently. In this retrospective study, we sought to determine the frequency and features of radiologic findings in the setting of a tertiary care center. We also noticed that some of our patients had simultaneous multiple conditions that were previously shown to cause PRES independently in the literature. These probable predisposing factors were also revisited. (C) 2007 Elsevier Ireland Ltd. All rights reserved.