Metabolomics and proteomics profiles of some medicinal plants and correlation with BDNF activity

Gonulalan E. M., NEMUTLU E., Bayazeid O., KOÇAK E., Yalcin F. N., DEMİREZER L. Ö.

PHYTOMEDICINE, vol.74, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 74
  • Publication Date: 2020
  • Doi Number: 10.1016/j.phymed.2019.152920
  • Journal Name: PHYTOMEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Keywords: Metabolomics, Proteomics, Medicinal plants, BDNF, GC-MS, LC-qTOF-MS, ST-JOHNS-WORT, VALERENIC ACID, VALERIAN EXTRACT
  • Hacettepe University Affiliated: Yes


Background: Identification of the low abundance of phytochemicals in plant extracts is very difficult. Pharmacological activity observed in such plants is not due to a single compound. In most cases, plant extracts show activity based on synergistic or antagonistic effects. Therefore, the idea of a holistic approach is more rational.