Metabolomics and proteomics profiles of some medicinal plants and correlation with BDNF activity

Gonulalan E. M., NEMUTLU E., Bayazeid O., KOÇAK E., Yalcin F. N., DEMİREZER L. Ö.

PHYTOMEDICINE, cilt.74, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 74
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.phymed.2019.152920
  • Dergi Adı: PHYTOMEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Anahtar Kelimeler: Metabolomics, Proteomics, Medicinal plants, BDNF, GC-MS, LC-qTOF-MS, ST-JOHNS-WORT, VALERENIC ACID, VALERIAN EXTRACT
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Identification of the low abundance of phytochemicals in plant extracts is very difficult. Pharmacological activity observed in such plants is not due to a single compound. In most cases, plant extracts show activity based on synergistic or antagonistic effects. Therefore, the idea of a holistic approach is more rational.