PTPN22 gene polymorphism in Takayasus arteritis

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Sahin N., AKSU K., Kamali S., Bicakcigil M., Oezbalkan Z., Fresko I., ...More

RHEUMATOLOGY, vol.47, no.5, pp.634-635, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 5
  • Publication Date: 2008
  • Doi Number: 10.1093/rheumatology/ken106
  • Journal Name: RHEUMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.634-635
  • Hacettepe University Affiliated: Yes


Objective. Takayasus arteritis (TA) is a chronic, rare granulomatous panarteritis of unknown aetiology involving mainly the aorta and its major branches. In this study, genetic susceptibility to TA has been investigated by screening the functional single nucleotide polymorphism (SNP) of PTPN22 gene encoding the lymphoid-specific protein tyrosine phosphatase.