Crystal structure of 2-[2-(2,5-dichlorobenzyloxy)-2-(furan-2-yl) ethyl]-2H-indazole

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Guven O. O., Turk G., Adler P. D. F., Coles S. J., HÖKELEK T.

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, vol.72, pp.1377-1384, 2016 (ESCI) identifier identifier identifier


In the title compound, C20H16Cl2N2O2, the indazole ring system is approximately planar [maximum deviation = 0.033 (1) angstrom], its mean plane is oriented at dihedral angles of 25.04 (4) and 5.10 (4)degrees to the furan and benzene rings, respectively. In the crystal, pairs of C-H-ind center dot center dot center dot O-bo (ind = indazole and bo = benzyloxy) hydrogen bonds link the molecules into centrosymmetric dimers with graph-set motif R-2(2) (12). Weak C-H center dot center dot center dot pi interactions is also observed. Aromatic pi-pi stacking between the benzene and the pyrazole rings from neighbouring molecules [centroid-centroid distance = 3.8894 (7) angstrom] further consolidates the crystal packing.