Synthesis and antimicrobial activity of 1,4-diaryl-2-azetidinones
FARMACO, vol.55, no.2, pp.147-150, 2000 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 55 Issue: 2
- Publication Date: 2000
- Doi Number: 10.1016/s0014-827x(99)00126-3
- Journal Name: FARMACO
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.147-150
- Hacettepe University Affiliated: Yes
Abstract
Cycloaddition of substituted 4,4-benzylidene-anilines to in situ prepared dichloroketenes in the presence of dichloroacetyl chloride and triethylamine affords a variety of 2-azetidinones. All the compounds were characterized by IR and H-1 NMR. Their antimicrobial activity, against Gram(+) and Gram(-) bacteria and fungi, was tested. (C) 2000 Elsevier Science S.A. All rights reserved.