Synthesis and antimicrobial activity of 1,4-diaryl-2-azetidinones

Guner V., Yildirir S., Ozcelik B., Abbasoglu U.

FARMACO, cilt.55, sa.2, ss.147-150, 2000 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 55 Sayı: 2
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1016/s0014-827x(99)00126-3
  • Dergi Adı: FARMACO
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.147-150
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Cycloaddition of substituted 4,4-benzylidene-anilines to in situ prepared dichloroketenes in the presence of dichloroacetyl chloride and triethylamine affords a variety of 2-azetidinones. All the compounds were characterized by IR and H-1 NMR. Their antimicrobial activity, against Gram(+) and Gram(-) bacteria and fungi, was tested. (C) 2000 Elsevier Science S.A. All rights reserved.