Synthesis and antimicrobial activity of 1,4-diaryl-2-azetidinones


Guner V., Yildirir S., Ozcelik B., Abbasoglu U.

FARMACO, cilt.55, ss.147-150, 2000 (SCI İndekslerine Giren Dergi) identifier

Özet

Cycloaddition of substituted 4,4-benzylidene-anilines to in situ prepared dichloroketenes in the presence of dichloroacetyl chloride and triethylamine affords a variety of 2-azetidinones. All the compounds were characterized by IR and H-1 NMR. Their antimicrobial activity, against Gram(+) and Gram(-) bacteria and fungi, was tested. (C) 2000 Elsevier Science S.A. All rights reserved.