Atıf İçin Kopyala
Erdogan S., Medarova Z. O., Roby A., Moore A., Torchilin V. P.
JOURNAL OF MAGNETIC RESONANCE IMAGING, cilt.27, sa.3, ss.574-580, 2008 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
27
Sayı:
3
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Basım Tarihi:
2008
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Doi Numarası:
10.1002/jmri.21202
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Dergi Adı:
JOURNAL OF MAGNETIC RESONANCE IMAGING
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.574-580
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Anahtar Kelimeler:
tumor imaging, MRI, liposome, polychelating, amphihilic polymer, 2C5 antibody, T1 mapping, CONTRAST AGENTS, ANTIBODIES, IDENTIFICATION, DELIVERY, LIGANDS, BINDING
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Hacettepe Üniversitesi Adresli:
Evet
Özet
Purpose: To significantly enhance tumor MR imaging by using a contrast agent combining three components-a long-circulating liposome, liposomal membrane-incorporated polychelating amphiphilic polymer heavily loaded with gadolinium, and cancer-specific monoclonal antibody 2C5 attached to the liposome surface.