Comparison of the effects of high and low-moderate load lower limb resistance training on muscle strength and exercise capacity in individuals with COPD: A systematic review and meta-analysis

TOPCUOĞLU C., SAĞLAM M., Yağlı N. V.

Heart and Lung, cilt.64, ss.107-116, 2024 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 64
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1016/j.hrtlng.2023.12.003
  • Dergi Adı: Heart and Lung
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE
  • Sayfa Sayıları: ss.107-116
  • Anahtar Kelimeler: Chronic obstructive pulmonary disease, Exercise capacity, High load resistance training, Low-moderate load resistance training, Meta-analysis, Muscle strength
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Extrapulmonary changes also occur in COPD. Resistance training can increase muscle strength and exercise capacity. Objective: The objective of this systematic review was to examine and compare the effectiveness of high and low-moderate load lower limb resistance training on muscle strength and exercise capacity in individuals with stable chronic obstructive pulmonary disease (COPD). Methods: The PubMed/Medline, Scopus, Cochrane Library, ClinicalTrials.gov, Web of Science, EBSCO, and CINAHL databases were searched to identify the articles published in English between January 1970 and July 2023. Results: Seven randomized controlled trials with a total of 188 individuals with COPD (RT: 100, CG: 88) met the inclusion criteria. A significant difference was revealed (favoring high load) in the change in knee extensor muscle strength and leg press strength in the high load resistance training group compared to the low-moderate load resistance training group (MD 21.90 Nm, 95 % CI 17.46–26.34 Nm, p < 0.00001; MD 5.80 kg, 95 % CI 3.87–7.73 kg, p < 0.00001). A significant difference was observed in the change in 6 MWT (six minute walk test) distance (favoring low-moderate load) and VO2peak (peak oxygen uptake) (favoring high load) in the high load resistance training group compared to the low-moderate load resistance training group (MD -16.90 m, 95 % CI -29.76- -4.04 m, p < 0.010; MD 3.10 ml/kg/min, 95 % CI 2.65–3.55 ml/kg/min, p < 0.00001). Conclusion: This systematic review and meta-analysis demonstrated that both high-load and low-moderate load resistance training increased muscle strength and might increase exercise capacity.