Thrombocytopenia and emperipolesis in a patient with hepatitis A infection

Avci Z., Turul T., Catal F., Olgar E., BAYKAN A., Teksam O., ...More

PEDIATRIC HEMATOLOGY AND ONCOLOGY, vol.19, no.1, pp.67-70, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 1
  • Publication Date: 2002
  • Doi Number: 10.1080/088800102753356211
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.67-70
  • Hacettepe University Affiliated: Yes


Immune thrombocytopenia is a benign, self-limiting disease in children, responding well to treatment and generally associated with viral infections. A 13-year-old girl was admitted to a hospital with the epistaxis and propura after an attack of jaundice 6 weeks before. The diagnosis of hepatitis A virus (HAV)-induced thrombocytopenia was made. Furthermore, erythrophagocytosis by megakaryocytes was demonstrated in the bone marrow of the patient. Although hematologic complications following hepatitis B and C viruses are commonly reported, the association of hepatitis A vir-us and thrombocytopenia has rarely been described.