Serum elevated gamma glutamyltransferase levels may be a marker for oxidative stress in Alzheimer's disease

DOĞU B. B., Yavuz B., HALİL M. G., CANKURTARAN M., Ulger Z., Cankurtaran E. S., ...Daha Fazla

INTERNATIONAL PSYCHOGERIATRICS, cilt.20, sa.4, ss.815-823, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 4
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1017/s1041610208006790
  • Dergi Adı: INTERNATIONAL PSYCHOGERIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Sayfa Sayıları: ss.815-823
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Gamma glutamyltransferase (GGT) plays a role in cellular glutathione uptake, which is an important element of antioxidant mechanisms. An increase in serum GGT is thought to be an early and sensitive marker of oxidative stress. Oxidative stress has a role in the pathogenesis of Alzheimer's disease (AD). The aim of this study was to investigate the GGT levels in AD.