Serum elevated gamma glutamyltransferase levels may be a marker for oxidative stress in Alzheimer's disease

DOĞU B. B., Yavuz B., HALİL M. G., CANKURTARAN M., Ulger Z., Cankurtaran E. S., ...More

INTERNATIONAL PSYCHOGERIATRICS, vol.20, no.4, pp.815-823, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 4
  • Publication Date: 2008
  • Doi Number: 10.1017/s1041610208006790
  • Journal Name: INTERNATIONAL PSYCHOGERIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Page Numbers: pp.815-823
  • Hacettepe University Affiliated: Yes

Abstract

Background: Gamma glutamyltransferase (GGT) plays a role in cellular glutathione uptake, which is an important element of antioxidant mechanisms. An increase in serum GGT is thought to be an early and sensitive marker of oxidative stress. Oxidative stress has a role in the pathogenesis of Alzheimer's disease (AD). The aim of this study was to investigate the GGT levels in AD.