The effect of Bongardia Chrysogonum on prostate tissue in a rat model of STZ-induced diabetes

DOKUYUCU R., Gozukara K. H., ÖZCAN O., Sefil N. K., NACAR A., Dokuyucu A., ...More

SPRINGERPLUS, vol.5, 2016 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 5
  • Publication Date: 2016
  • Doi Number: 10.1186/s40064-016-2973-z
  • Journal Name: SPRINGERPLUS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Hacettepe University Affiliated: Yes

Abstract

Background: Bongardia chrysogonum is widely used in Turkey for treating urinary tract infections and prostate hypertrophy, and it also has potent hypoglycemic effects and aids glucose homeostasis. Because of the inflammatory conditions in diabetes mellitus (DM), the prostate tissue of men with diabetes is particularly susceptible to developing hypoplasia, and DM produces characteristic pathological changes in prostate tissue. Here, we examined the effects of B. chrysogonum on the prostate tissue of rats with streptozotocin (STZ)-induced diabetes.