Plasma 8-isoPGF2 alpha and serum melatonin levels in patients with minimal cognitive impairment and Alzheimer disease
TURKISH JOURNAL OF MEDICAL SCIENCES, vol.45, no.5, pp.1073-1077, 2015 (SCI-Expanded, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 45 Issue: 5
- Publication Date: 2015
- Doi Number: 10.3906/sag-1406-134
- Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Page Numbers: pp.1073-1077
- Hacettepe University Affiliated: Yes
Abstract
Background/aim: F2 alpha-isoprostane is accepted as an oxidative stress indicator and melatonin shows neuroprotective effects by antioxidative and antiamyloidogenic influences. By measuring these in patients diagnosed with minimal cognitive impairment (MCI) and Alzheimer-type dementia, we intended to demonstrate whether the measurement of these markers contributes to early diagnosis of Alzheimer disease (AD) in the MCI stage or not.