Plasma 8-isoPGF2 alpha and serum melatonin levels in patients with minimal cognitive impairment and Alzheimer disease
TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.45, sa.5, ss.1073-1077, 2015 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 45 Sayı: 5
- Basım Tarihi: 2015
- Doi Numarası: 10.3906/sag-1406-134
- Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.1073-1077
- Hacettepe Üniversitesi Adresli: Evet
Özet
Background/aim: F2 alpha-isoprostane is accepted as an oxidative stress indicator and melatonin shows neuroprotective effects by antioxidative and antiamyloidogenic influences. By measuring these in patients diagnosed with minimal cognitive impairment (MCI) and Alzheimer-type dementia, we intended to demonstrate whether the measurement of these markers contributes to early diagnosis of Alzheimer disease (AD) in the MCI stage or not.