Organic polymer-based monolithic capillary columns and their applications in food analysis

AYDOĞAN C., Gokaltun A., DENİZLİ A., El-Rassi Z.

JOURNAL OF SEPARATION SCIENCE, vol.42, no.5, pp.962-979, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 42 Issue: 5
  • Publication Date: 2019
  • Doi Number: 10.1002/jssc.201801051
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.962-979
  • Hacettepe University Affiliated: Yes


In recent years, the use of organic polymer monolithic capillary columns in separation science has gained popularity due to the fact that they are easy to fabricate and do not require retaining frits. These materials have been applied in different fields including foods, proteomics, and pharmaceuticals. The interest in food analysis still needs to develop in order to increase the sensitivity towards micro/nano-scale food applications for food samples of < 5 mu g (e.g., foodomics). In this regard, polymer monolithic capillary columns offer great separation capability in the food analytical separation science. We review the most important applications in food analysis using polymer monolithic capillary columns. In addition, several examples of the use of capillary separation methods combined with mass spectrometry detection in food analysis are summarized.