The acute effect of cervical mobilization on balance in patients with multiple sclerosis: a single-blind, randomized, controlled trial


Neurological Research, vol.46, no.1, pp.65-71, 2023 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 1
  • Publication Date: 2023
  • Doi Number: 10.1080/01616412.2023.2257455
  • Journal Name: Neurological Research
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS
  • Page Numbers: pp.65-71
  • Keywords: balance, cervical mobilization, Multiple sclerosis, neurological rehabilitation, vestibular system
  • Hacettepe University Affiliated: Yes


The cervical region plays an important role in providing proprioceptive and vestibular input to the postural control system. Objective. To investigate the effect of cervical mobilization on balance in multiple sclerosis (MS) patients. Methods. The study was undertaken at the neurological rehabilitation unit with 36 MS participants who were assigned randomly to the study (n = 18) and control group (n = 18). While the study group received a single session of 15 minutes of cervical and soft tissue mobilization, no intervention was applied to the control group to investigate the learning effect of the assessment. Patients were evaluated using Computerized Dynamic Posturography (CDP) (Sensory Organization Test (SOT), Limits of Stability (LoS), and Adaptation Test (ADT)), which reflects postural stability. Results. In the study group, a treatment effect was found on the vestibular ratio (VEST) score (p < 0.001) and the composite score of SOT (p = 0.002). Improvements were achieved in all parameters of the LoS and ADT in the study group. There was no statistically significant difference in terms of CDP results in the control group. Conclusion. Cervical mobilization has beneficial effects on balance in MS patients. Our findings support that cervical mobilization can be included in MS balance rehabilitation programs.