New phenylethanoid glycosides from Veronica pectinata var. glandulosa and their free radical scavenging activities


Saracoglu I. , HARPUT U. , INOUE M., OGIHARA Y.

CHEMICAL & PHARMACEUTICAL BULLETIN, cilt.50, ss.665-668, 2002 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 50 Konu: 5
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1248/cpb.50.665
  • Dergi Adı: CHEMICAL & PHARMACEUTICAL BULLETIN
  • Sayfa Sayıları: ss.665-668

Özet

A known phenylethanoid glycoside, ehrenoside (1), was isolated together with three new phenylethanoid glycosides, verpectoside A (2), B (3) and C (4) from the aerial parts of Veronica pectinata var. glandulosa. On the basis of spectral analysis (UV, FAB-MS, H-1-, C-13- and 2D-NMR), compounds 2-4 were determined to be 2-(3,4-dihydroxyphenyl)ethyl-O-alpha-L-arabinopyranosyl-(1 -->2)-[alpha-L-rhamnopyranosyl-(1-->3)]-(4-O-trans-feruloyl)-beta-D-glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl-O-beta-D-glucopyranosyl-(1-->2)- [alpha-L-rhamnopyranosyl-(1-->3)] (4-O-trans-caffeoyl)-beta-D-glucopyranoside and 2-(3,4-dihydroxyphenyl)ethyl-O-beta-D-glucopyranosyl-(1-->2)-[alpha-L-rhamnopyranosyl-(1-->3)](4-O-trans-feruloyl)-beta-D-glucopyranoside, respectively. Isolated phenylethanoid glycosides exhibited potent radical scavenging activity against the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical.