Improving characterization and diagnosis quality of myofascial pain syndrome: a systematic review of the clinical and biomarker overlap with delayed onset muscle soreness

Vadasz B., Gohari J., West D. W., Grosman-Rimon L., Wright E., ÖZÇAKAR L., ...More

EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE, vol.56, no.4, pp.469-478, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 56 Issue: 4
  • Publication Date: 2020
  • Doi Number: 10.23736/s1973-9087.20.05820-7
  • Journal Name: EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE
  • Page Numbers: pp.469-478
  • Keywords: Myofascial pain syndromes, Myalgia, Biomarkers, Trigger point, SPONTANEOUS ELECTRICAL-ACTIVITY, HUMAN SKELETAL-MUSCLE, NERVE GROWTH-FACTOR, ECCENTRIC EXERCISE, TRIGGER POINTS, TRAPEZIUS MYALGIA, INFLAMMATORY RESPONSES, NEUTROPHIL ACTIVATION, CENTRAL SENSITIZATION, OXIDATIVE STRESS
  • Hacettepe University Affiliated: Yes

Abstract

INTRODUCTION: Myofascial pain syndrome (MPS) is one of the most common conditions of chronic musculoskeletal pain, yet its mechanisms are still poorly understood. Delayed Onset Muscle Soreness (DOMS) is also a regional pain syndrome that has clinical similarities to MPS, but has been better investigated. Emerging research suggests that DOMS may be a valid experimental model for studying MPS; however, a comparison of the similarities and differences of these two conditions has previously not been performed. Herein, we aimed to identify the similarities and differences in the clinical features and biomarkers between DOMS and MPS in order to better define MPS and identify future areas of (DOMS-informed) MPS research.