Pituitary Gland Metastasis of Breast Cancer: A Case Report

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Ozkan C., ARSLAN Ç., KILIÇ M., ERMAN M., Altundag K.

UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI, vol.22, no.1, pp.42-45, 2012 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 1
  • Publication Date: 2012
  • Doi Number: 10.4999/uhod.09127
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.42-45
  • Hacettepe University Affiliated: Yes


Pituitary gland is an uncommon site of metastasis for malignancies. However, breast cancer is the most common primary metastasizing to hypophysis in women. It may cause hormonal problems in different patterns due to mass affect and invasion to pituitary gland. We present a 53-year-old woman with HER-2 positive breast cancer presenting with intermittent symptoms of diabetes insipidus and rapidly developing pituitary mass treated with transsphenoidal surgery and thereafter the recurrent lesion with cyberknife stereotactic radiotherapy and systemic chemotherapy.