Local granulocyte-macrophage colony-stimulating factor improves incisional wound healing in adriamycin-treated rats
SURGERY TODAY, cilt.36, sa.1, ss.47-51, 2006 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 36 Sayı: 1
- Basım Tarihi: 2006
- Doi Numarası: 10.1007/s00595-005-3097-1
- Dergi Adı: SURGERY TODAY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.47-51
- Hacettepe Üniversitesi Adresli: Hayır
Özet
Purpose. Neoadjuvant treatment is often given for locally advanced malignancies; however, clinical and experimental studies have shown that some chemotherapeutic agents impair wound healing. It has been reported that granulocyte-macrophage colony-stimulating factor (GM-CSF) applied locally improves dermal wound healing. Thus, we investigated the effects of locally injected GM-CSF on abdominal wounds impaired by adriamycin, a widely used chemotherapeutic agent.