CURRENT OPINION IN RHEUMATOLOGY, vol.18, no.1, pp.108-117, 2006 (SCI-Expanded)
Purpose of review The aim of this article is to summarize recent clinical genetic and pathophysiological findings of familial Mediterranean fever and several of the other systemic autoinflammatory diseases, a recently recognized group of disorders characterized by seemingly unprovoked inflammation but lacking high-titer autoantibodies. Genetic and clinical tools are improving the ability of the clinician to better approach patients with periodic fever and inflammation.