Familial Mediterranean fever and the other autoinflammatory syndromes: evaluation of the patient with recurrent fever

Samuels J., Ozen S.

CURRENT OPINION IN RHEUMATOLOGY, vol.18, no.1, pp.108-117, 2006 (SCI-Expanded) identifier identifier identifier


Purpose of review The aim of this article is to summarize recent clinical genetic and pathophysiological findings of familial Mediterranean fever and several of the other systemic autoinflammatory diseases, a recently recognized group of disorders characterized by seemingly unprovoked inflammation but lacking high-titer autoantibodies. Genetic and clinical tools are improving the ability of the clinician to better approach patients with periodic fever and inflammation.