The hydroxylation of omeprazole correlates with S-mephenytoin and proguanil metabolism

Kortunay, S; Basci, NURSABAH; Bozkurt, A; Isimer, A; Sayal, A; Kayaalp, SO

doi:10.1007/s002280050373

The hydroxylation of omeprazole correlates with S-mephenytoin and proguanil metabolism

Kortunay S., Basci N. E., Bozkurt A., Isimer A., Sayal A., Kayaalp S.

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, vol.53, pp.261-264, 1997 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 53
Publication Date: 1997
Doi Number: 10.1007/s002280050373
Journal Name: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.261-264
Hacettepe University Affiliated: Yes

Abstract

Objectives: This pharmacogenetic study was aimed at studying the pattern of oxidation of omeprazole in a Turkish population and testing whether omeprazole metabolism cosegregates with the genetically determined metabolism of mephenytoin and proguanil in Turkish subjects.