The hydroxylation of omeprazole correlates with S-mephenytoin and proguanil metabolism

Kortunay S., Basci N. E., Bozkurt A., Isimer A., Sayal A., Kayaalp S.

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, cilt.53, ss.261-264, 1997 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 53
  • Basım Tarihi: 1997
  • Doi Numarası: 10.1007/s002280050373
  • Dergi Adı: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.261-264
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Objectives: This pharmacogenetic study was aimed at studying the pattern of oxidation of omeprazole in a Turkish population and testing whether omeprazole metabolism cosegregates with the genetically determined metabolism of mephenytoin and proguanil in Turkish subjects.