Different cell sizes in human limbal and central corneal basal epithelia measured by confocal microscopy and flow cytometry


Romano A., Espana E., Yoo S., Budak M. T. , Wolosin J., Tseng S.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, cilt.44, ss.5125-5129, 2003 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 44 Konu: 12
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1167/iovs.03-0628
  • Dergi Adı: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
  • Sayfa Sayıları: ss.5125-5129

Özet

PURPOSE. In the epidermis, the highest clonogenicity, a feature of stem cells (SCs), is found in the smallest keratinocyte. In the limbal-corneal (LC) epithelium the SCs are exclusively localized in the basal epithelial layer of the limbal domain. The current study was conducted to determine whether this spatial SC arrangement is reflected in differences in the cell size between limbal and corneal cells.