Different cell sizes in human limbal and central corneal basal epithelia measured by confocal microscopy and flow cytometry

Romano A., Espana E., Yoo S., Budak M. T., Wolosin J., Tseng S.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, cilt.44, sa.12, ss.5125-5129, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 12
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1167/iovs.03-0628
  • Dergi Adı: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.5125-5129
  • Hacettepe Üniversitesi Adresli: Hayır

Özet

PURPOSE. In the epidermis, the highest clonogenicity, a feature of stem cells (SCs), is found in the smallest keratinocyte. In the limbal-corneal (LC) epithelium the SCs are exclusively localized in the basal epithelial layer of the limbal domain. The current study was conducted to determine whether this spatial SC arrangement is reflected in differences in the cell size between limbal and corneal cells.