Demonstrating the potential role of a cerebral blood flow monitor during cardiac surgery with hypothermic circulatory arrest

Zavriyev A. I., KAYA K., Farzam P., Farzam P. Y., Sunwoo J., Jassar A. S., ...Daha Fazla

SPIE, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics, Boston, Amerika Birleşik Devletleri, 06 Mart 2021, (Tam Metin Bildiri)

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Doi Numarası: 10.1117/12.2578758
  • Basıldığı Şehir: Boston
  • Basıldığı Ülke: Amerika Birleşik Devletleri
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Real-time noninvasive cerebral blood flow monitoring during cardiac surgery could decrease rates of neurologic injury associated with hypothermic circulatory arrests (HCA). We used combined frequency domain near-infrared spectroscopy and diffuse correlation spectroscopy (FDNIRS-DCS) to measure cerebral oxygen saturation and an index of blood flow (CBFi) in 12 adults undergoing HCA. Our measurements revealed negligible CBFi during retrograde cerebral perfusion (RCP: CBFi 91.2%±3.3% drop; HCA-only: 95.5%±1.8% drop). There was a significant difference during antegrade cerebral perfusion (p = 0.003). We conclude that FDNIRS-DCS can be a powerful tool to optimize cerebral perfusion and that RCP’s efficacy needs to be further examined.