Demonstrating the potential role of a cerebral blood flow monitor during cardiac surgery with hypothermic circulatory arrest

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Zavriyev A. I., KAYA K., Farzam P., Farzam P. Y., Sunwoo J., Jassar A. S., ...More

SPIE, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics, Boston, United States Of America, 06 March 2021, (Full Text)

• Publication Type: Conference Paper / Full Text
• Doi Number: 10.1117/12.2578758
• City: Boston
• Country: United States Of America
• Hacettepe University Affiliated: Yes

Abstract

Real-time noninvasive cerebral blood flow monitoring during cardiac surgery could decrease rates of neurologic injury associated with hypothermic circulatory arrests (HCA). We used combined frequency domain near-infrared spectroscopy and diffuse correlation spectroscopy (FDNIRS-DCS) to measure cerebral oxygen saturation and an index of blood flow (CBFi) in 12 adults undergoing HCA. Our measurements revealed negligible CBFi during retrograde cerebral perfusion (RCP: CBFi 91.2%±3.3% drop; HCA-only: 95.5%±1.8% drop). There was a significant difference during antegrade cerebral perfusion (p = 0.003). We conclude that FDNIRS-DCS can be a powerful tool to optimize cerebral perfusion and that RCP’s efficacy needs to be further examined.