Genotype/Phenotype Correlation in Nephrotic Syndrome Caused by WT1 Mutations


Chernin G., Vega-Warner V., Schoeb D. S. , Heeringa S. F. , Ovunc B., Saisawat P., ...More

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, vol.5, no.9, pp.1655-1662, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 5 Issue: 9
  • Publication Date: 2010
  • Doi Number: 10.2215/cjn.09351209
  • Title of Journal : CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
  • Page Numbers: pp.1655-1662

Abstract

Background and objectives: The risk of developing Wilms tumor (WT) can be present or absent in patients with nephrotic syndrome (NS) caused by WT1 mutations. Here, the genotype/phenotype correlation regarding the outcome and risk for WT in 52 patients from 51 families with NS due to WT1 mutations is described.