Acute Budd-Chiari syndrome associated with activated protein C resistance during intravenous anticoagulant treatment

YILDIZ O. B. , Oran B., Buyukasik Y., Haznedaroglu I., Cekirge S., Kirazli S.

CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, cilt.4, ss.220-223, 1998 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 4 Konu: 3
  • Basım Tarihi: 1998
  • Doi Numarası: 10.1177/107602969800400315
  • Sayfa Sayıları: ss.220-223


The Budd-Chiari syndrome is a rare but serious condition defined as hepatic venous outflow obstruction. This article presents a case of acute Budd-Chiari syndrome in a 13-year-old woman with activated protein C resistance while she was bring treated with intravenous heparin infusion for previously documented deep venous thrombosis. Activated protein C resistance caused by factor V Leiden mutation has emerged as the most prevalent hereditary cause of venous thromboembolism and should be considered as an etiologic factor in patients with Budd-Chiari syndrome.