Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans


Levine S., Nguyen T., Taylor N., Friscia M. E. , Budak M. T. , Rothenberg P., ...Daha Fazla

NEW ENGLAND JOURNAL OF MEDICINE, cilt.358, ss.1327-1335, 2008 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 358 Konu: 13
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1056/nejmoa070447
  • Dergi Adı: NEW ENGLAND JOURNAL OF MEDICINE
  • Sayfa Sayıları: ss.1327-1335

Özet

Background: The combination of complete diaphragm inactivity and mechanical ventilation (for more than 18 hours) elicits disuse atrophy of myofibers in animals. We hypothesized that the same may also occur in the human diaphragm.