Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans

Levine S., Nguyen T., Taylor N., Friscia M. E., Budak M. T., Rothenberg P., ...Daha Fazla

NEW ENGLAND JOURNAL OF MEDICINE, cilt.358, sa.13, ss.1327-1335, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 358 Sayı: 13
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1056/nejmoa070447
  • Dergi Adı: NEW ENGLAND JOURNAL OF MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1327-1335
  • Hacettepe Üniversitesi Adresli: Hayır

Özet

Background: The combination of complete diaphragm inactivity and mechanical ventilation (for more than 18 hours) elicits disuse atrophy of myofibers in animals. We hypothesized that the same may also occur in the human diaphragm.