Microtensile bond strengths of In-Ceram Alumina cores veneered with two ceramics after different numbers of firing cycles were evaluated. After In-Ceram Alumina cores were fabricated, they were veneered with either Vitadur Alpha or Vita VM7. A control group of each core-veneer combination was fired twice, and a second group was fired five times to induce thermal fatigue. Obtained microbars were subjected to microtensile bond strength tests. Data were analyzed using two-way analysis of variance. Microtensile bond strength values for Vita VM7 specimens were higher than those for Vitadur Alpha (P < .001). Although the number of firing cycles revealed no change in bond strength, the veneering material proved to be an important factor. Int J Prosthodont 2011;24:515-516.