Molecular characterization of glucose-6-phosphate dehydrogenase deficiency in Turkey

Oner R., Gumruk F., Acar C., Oner C., Gurgey A., Altay C.

HAEMATOLOGICA, cilt.85, ss.320-321, 2000 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 85 Konu: 3
  • Basım Tarihi: 2000
  • Sayfa Sayıları: ss.320-321


Molecular pathology of glucose-6-phosphate dehydrogenase (G6PD) was studied in 50 unrelated red cell G6PD deficient Turkish males. DNA analysis of G6PD genes revealed that 40 of the 50 subjects (80%) had G6PD B- 563T, 2 subjects (4%) A- (376G/202A) and one subject (2%) G6PD Chatam (1003A). The remaining 7 subjects (14%) did not have any of these three mutations.