Isolated Bone Metastases in Early Stage Endometrial Adenocarcinoma: A Case Report and Review of the Literature

Kurt M., KILIÇKAP S., AKSOY S., ERMAN M., Gedikoglu G., Turker A.

UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI, vol.21, no.1, pp.52-56, 2011 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 1
  • Publication Date: 2011
  • Doi Number: 10.4999/uhod.09024
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.52-56
  • Hacettepe University Affiliated: Yes


Isolated skeletal metastasis of endometrial carcinoma is very unusual. Herein, we report a 62-year-old woman diagnosed as FIGO stage IC, grade I, endometrial carcinoma who was found to have isolated femur and tibia metastases just after completing local radiotherapy. Incisional biopsy revealed metastatic adenocarcinoma. Following radiotherapy, medroxyprogesterone acetate and zoledronic acid was given. After a month, spontaneous right proximal femur fracture occurred and new bone metastasis was detected. Local radiotherapy and six cycles of paclitaxel and carboplatin were given; however, during a 3-year follow-up, bone metastases progressed. We review the endometrial carcinoma with bone metastasis in literature.