Hematopoietic Stem Cell Transplantation as Treatment for Patients with DOCK8 Deficiency


Aydin S. E. , Freeman A. F. , Al-Herz W., Al-Mousa H. A. , Arnaout R. K. , Aydin R. C. , ...Daha Fazla

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, cilt.7, ss.848-855, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 7 Konu: 3
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.jaip.2018.10.035
  • Dergi Adı: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
  • Sayfa Sayıları: ss.848-855

Özet

BACKGROUND: Biallelic variations in the dedicator of cytokinesis 8 (DOCK8) gene cause a combined immunodeficiency with eczema, recurrent bacterial and viral infections, and malignancy. Natural disease outcome is dismal, but allogeneic hematopoietic stem cell transplantation (HSCT) can cure the disease.