Effect of low-dose N-acetyl-cysteine infusion on tourniquet-induced ischaemia-reperfusion injury in arthroscopic knee surgery


Saricaoglu F., Dal D., Salman A., Atay O. , Doral M. , Salman M., ...Daha Fazla

ACTA ANAESTHESIOLOGICA SCANDINAVICA, cilt.49, ss.847-851, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 49 Konu: 6
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1111/j.1399-6576.2005.00722.x
  • Dergi Adı: ACTA ANAESTHESIOLOGICA SCANDINAVICA
  • Sayfa Sayıları: ss.847-851

Özet

Background: Temporary occlusion of blood flow is used during arthroscopic knee surgery in order to provide a bloodless surgical field. The resulting ischaemia-reperfusion causes lipid peroxidation, which contributes to tissue injury. The aim of the study was to investigate the effect of low-dose n-acetyl cysteine (NAC) infusion on oxidative stress by determining malondialdehyde (MDA) levels during arthroscopic knee surgery.