Effect of low-dose N-acetyl-cysteine infusion on tourniquet-induced ischaemia-reperfusion injury in arthroscopic knee surgery

Saricaoglu F., Dal D., Salman A., Atay O., Doral M., Salman M., ...Daha Fazla

ACTA ANAESTHESIOLOGICA SCANDINAVICA, cilt.49, sa.6, ss.847-851, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 6
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1111/j.1399-6576.2005.00722.x
  • Dergi Adı: ACTA ANAESTHESIOLOGICA SCANDINAVICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.847-851
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Temporary occlusion of blood flow is used during arthroscopic knee surgery in order to provide a bloodless surgical field. The resulting ischaemia-reperfusion causes lipid peroxidation, which contributes to tissue injury. The aim of the study was to investigate the effect of low-dose n-acetyl cysteine (NAC) infusion on oxidative stress by determining malondialdehyde (MDA) levels during arthroscopic knee surgery.