The study was conducted to evaluate the relationship between compliance of Type 2 Diabetes patients with the Mediterranean Diet and their quality of life. A total of 200 patients admitted to TRNC Famagusta State Hospital Internal Medicine Clinic, diagnosed with Type 2 Diabetes, between the ages of 30-65 were included in the study. Patients filled out questionnaires that included data on demographic characteristics along with a 14-item MEDAS questionnaire, and SF-36 Quality of Life Scale. A total of 45% of patients were male, 55% female, mean age was 55 +/- 8.28, and 65.6% of males and 49.1% of females complied moderately with the Mediterranean Diet (MEDAS score 6-9). According to the physical and mental indicator score, the quality of life of patients was moderate, and a strong relation was detected between gender and quality of life (p < 0.001). The scores of the quality of life of males were higher than those of females. Men and women who had moderate compliance with the Mediterranean Diet had higher physical function scores than those who had low compliance. The quality of life can be increased with regular training on the importance of dietary compliance because of the positive effects of the Mediterranean Diet on health.