Performance of Various Commercial Assays for the Detection of Toscana Virus Antibodies

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ERGÜNAY K., Litzba N., Lo M. M., AYDOĞAN S., Saygan M. B., Us D., ...More

VECTOR-BORNE AND ZOONOTIC DISEASES, vol.11, no.6, pp.781-787, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 6
  • Publication Date: 2011
  • Doi Number: 10.1089/vbz.2010.0224
  • Journal Name: VECTOR-BORNE AND ZOONOTIC DISEASES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.781-787
  • Hacettepe University Affiliated: Yes

Abstract

Introduction: Sandfly fever virus (SFV) serotypes sandfly fever Naples virus, sandfly fever Sicilian virus, and sandfly fever Cyprus virus cause febrile diseases, whereas Toscana virus (TOSV) is responsible for aseptic meningoencephalitis. Diagnosis and surveillance of TOSV depend heavily on virus serology, and various commercial assays utilizing various antigen sources and formats have been available. The aim of this study was to perform comparative evaluation of commercially available serological assays for anti-TOSV immunoglobulins.