Is decreased bone mineral density associated with development of scoliosis? A bipedal osteopenic rat model

Creative Commons License

Dede O., Akel I., Demirkiran G., Yalcin N., Marcucio R., Acaroglu E.

SCOLIOSIS AND SPINAL DISORDERS, vol.6, 2011 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 6
  • Publication Date: 2011
  • Doi Number: 10.1186/1748-7161-6-24
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL
  • Hacettepe University Affiliated: Yes


Background: An association between adolescent idiopathic scoliosis and osteopenia has been proposed to exist. It is still not clear whether there is such an association and if so, whether osteopenia is a causative factor or a consequence. Our previous pilot studies have suggested the presence of osteopenia in scoliotic animals. The aim of this study was to investigate the development of scoliosis in an unpinealectomized bipedal osteopenic rat model, implementing osteoporosis as a causative factor.