Predictive factors for stem cell mobilization failure in multiple myeloma patients: A single center experience

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GÖKER H., Ciftciler R., DEMİROĞLU H., Turgut M., SAYINALP N., Haznedaroglu I. C., ...More

TRANSFUSION AND APHERESIS SCIENCE, vol.59, no.1, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.1016/j.transci.2019.06.023
  • Journal Name: TRANSFUSION AND APHERESIS SCIENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, Biotechnology Research Abstracts, EMBASE, MEDLINE
  • Hacettepe University Affiliated: Yes

Abstract

Background and aim: High-dose chemotherapy followed by autologous stem cell transplantation (ASCT) has been considered the standard of treatment care for patients with multiple myeloma (MM). Insufficient mobilization and harvest of peripheral stem cells can be a major obstacle for performing ASCT. This is resulting in a lacking opportunity of cure in patients with MM. The aim of this study was to evaluate the factors which influence mobilization failure in patients with MM.