Mechanism of action of the cisapride-induced vasodilatation in renal vasculature of rat


Tekes E., Bayar B., Emre-Aydingoz S., Tuncer M.

INDIAN JOURNAL OF MEDICAL RESEARCH, cilt.119, ss.115-120, 2004 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 119 Konu: 3
  • Basım Tarihi: 2004
  • Dergi Adı: INDIAN JOURNAL OF MEDICAL RESEARCH
  • Sayfa Sayıları: ss.115-120

Özet

Background & objectives: Cisapride is a prokinetic agent with cholinomimetic and 5-HT4 receptor agonistic properties. It has been proposed that cisapride-induced hypotension is partly mediated by cholinergic system. The aim of this study was to investigate the mechanism of cisapride-induced dilatation in the rat isolated perfused kidney.