Free oxygen radical-induced acute pancreatitis. A light and electron microscopic study

Coskun T., Korkusuz P., Kaya Y., Ors U., Aker Y., Kilinc K.

HEPATO-GASTROENTEROLOGY, vol.50, no.49, pp.43-48, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 49
  • Publication Date: 2003
  • Journal Name: HEPATO-GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.43-48
  • Hacettepe University Affiliated: Yes

Abstract

Background/Aims: To date, direct toxic, effects of free oxygen radicals in vivo on pancreatic parenchyma have not been studied thoroughly. We aimed to study: 1) the detailed histopathological changes induced by free oxygen radicals in pancreas; and 2) the preventive effect of intraductal catalase in H2O2-induced acute pancreatitis.