Azole-Resistance in Aspergillus terreus and Related Species: An Emerging Problem or a Rare Phenomenon?

Zoran, Tamara; Sartori, Bettina; Sappl, Laura; Aigner, Maria; Sanchez-Reus, Ferran; Rezusta, Antonio; Chowdhary, Anuradha; Taj-Aldeen, Saad; Arendrup, Maiken; Oliveri, Salvatore; Kontoyiannis, Dimitrios; Alastruey-Izquierdo, Ana; Lagrou, Katrien; Lo Cascio, Giuliana; Meis, Jacques; Buzina, Walter; Farina, Claudio; Drogari-Apiranthitou, Miranda; Grancini, Anna; Tortorano, Anna; Willinger, Birgit; Hamprecht, Axel; Johnson, Elizabeth; Klingspor, Lena; Arsic-Arsenijevic, Valentina; Cornely, Oliver; Meletiadis, Joseph; Prammer, Wolfgang; Tullio, Vivian; Vehreschild, Jorg-Janne; Trovato, Laura; Lewis, Russell; Segal, Esther; Rath, Peter-Michael; Hamal, Petr; Rodriguez-Iglesias, Manuel; Roilides, Emmanuel; Arikan-Akdagli, SEVTAP; Chakrabarti, Arunaloke; Colombo, Arnaldo; Fernandez, Mariana; Teresa Martin-Gomez, M.; Badali, Hamid; Petrikkos, Georgios; Klimko, Nikolai; Heimann, Sebastian; Uzun, ÖMRÜM; Roudbary, Maryam; de la Fuente, Sonia; Houbraken, Jos; Risslegger, Brigitte; Lass-Floerl, Cornelia; Lackner, Michaela

doi:10.3389/fmicb.2018.00516

Azole-Resistance in Aspergillus terreus and Related Species: An Emerging Problem or a Rare Phenomenon?

Zoran T., Sartori B., Sappl L., Aigner M., Sanchez-Reus F., Rezusta A., ...More

FRONTIERS IN MICROBIOLOGY, vol.9, 2018 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 9
Publication Date: 2018
Doi Number: 10.3389/fmicb.2018.00516
Journal Name: FRONTIERS IN MICROBIOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Open Archive Collection: AVESIS Open Access Collection
Hacettepe University Affiliated: Yes

Abstract

Objectives: Invasive mold infections associated with Aspergillus species are a significant cause of mortality in immunocompromised patients. The most frequently occurring aetiological pathogens are members of the Aspergillus section Fumigati followed by members of the section Terrei. The frequency of Aspergillus terreus and related (cryptic) species in clinical specimens, as well as the percentage of azole-resistant strains remains to be studied.